3-Piperidinecarboxylic acid t-butyl ester

3-Piperidinecarboxylic acid t-butyl ester - Names and Identifiers

Name	tert-butyl piperidine-3-carboxylate
Synonyms	TERT-BUTYL PIPERIDINE-3-CARBOXYLATE tert-butyl piperidine-3-carboxylate 3-Piperidinecarboxylic acid t-butyl ester tert-butyl piperidine-3-carboxylate.HCl salt 3-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER HCL tert-Butyl piperidine-3-carboxylate hydrochloride 3-Piperidinecarboxylic acid, 1,1-dimethylethyl ester RS-3-Piperidinecarboxylic acid1,1-dimethylethyl ester 3-Piperidinecarboxylic acid T-butyl ester hydrochloride Piperidine-3-carboxylic acid tert-butyl ester hydrochloride
CAS	301180-05-2
InChI	InChI=1/C10H19NO2/c1-10(2,3)13-9(12)8-5-4-6-11-7-8/h8,11H,4-7H2,1-3H3

3-Piperidinecarboxylic acid t-butyl ester - Physico-chemical Properties

Molecular Formula	C10H19NO2
Molar Mass	185.26
Density	0.976±0.06 g/cm3(Predicted)
Boling Point	241.0±33.0 °C(Predicted)
Flash Point	99.5°C
Vapor Presure	0.0369mmHg at 25°C
pKa	9.28±0.10(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.452

3-Piperidinecarboxylic acid t-butyl ester - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R51 - Toxic to aquatic organisms
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
Hazard Class	IRRITANT

3-Piperidinecarboxylic acid t-butyl ester - Introduction

tert-butyl piperidine-3-carboxylate is an organic compound with the chemical formula C12H23NO2. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless liquid or solid
-Melting point: About 20-22 degrees Celsius
-Boiling point: About 280-285 degrees Celsius
-Solubility: Soluble in organic solvents such as alcohols and ethers

Use:
- tert-butyl piperidine-3-carboxylate are commonly used as raw materials and intermediates in organic synthesis for the synthesis of other compounds.
-It is widely used in drug synthesis, such as the synthesis of precursor compounds for drugs and pesticides.

Method:
tert-butyl piperidine-3-carboxylate can be prepared by the following methods:
-Esterification of 3-piperidinol with tert-butyl chloroformate.
-3-piperidinecarboxylic acid is obtained by reacting with tert-butyl chloroformate.

Safety Information:
- tert-butyl piperidine-3-carboxylate may be irritating to the skin, eyes and respiratory tract and should be avoided. Wear protective gloves and glasses when using.
-During operation and storage, avoid exposure to open flames and high temperatures.
-Observe proper laboratory practices and store the compound properly. In case of accidental leakage or ingestion, seek medical help immediately.

Last Update：2024-04-09 15:17:56